UBN1 (1-190) Mouse Monoclonal Antibody [Clone ID: UBN1-02]

CAT#: AM26039PU-N

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UBN1 (1-190) mouse monoclonal antibody, clone UBN1-02, Aff - Purified



USD 292.00


Availability*
2 Weeks

Size
    • 100 ug


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Specifications

Product Data
Clone Name UBN1-02
Applications IP, WB
Recommended Dilution Immunoprecipitation.
Western blot: 1-5 μg/ml; Positive control: HeLa cell line.
Reactivity Human
Host Mouse
Isotype IgG
Clonality Monoclonal
Immunogen Recombinant protein corresponding to amino acids 1-190 of ubinuclein 1
Specificity This antibody recognizes N-terminal part of ubinuclein 1 (UBN1), a widely expressed nuclear and adhesion complex protein. Western blotting analysis reveals UBN1 as a 165 kDa band.
Formulation Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
Conjugation Unconjugated
Storage Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens ubinuclein 1 (UBN1), transcript variant 1
Background Ubinuclein 1 (UBN1) is a ubiquitously expressed evolutionarily conserved protein which binds to proliferation-promoting genes that are repressed by formation of senescence-associated heterochromatin foci (SAHF). Ubinuclein 1 associates with various transcription factors and with histone methyltransferase activity, is indispensable for SAHF formation and appears to be a regulator of senescence. Although in most cells ubinuclein is localized to the nucleus, in cells forming tight junctions it is recruited to the cell adhesion complexes, dependently on the cell density.
Synonyms VT; VT4
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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