KIR2DL4 Mouse Monoclonal Antibody [Clone ID: mAb#33]

SKU AM26033PU-N

KIR2DL4 mouse monoclonal antibody, clone mAb#33, Aff - Purified

Product Data

• Clone Name: mAb#33
• Application: FC, FN, IF, IP
• Recommended Dilution: Immunoprecipitation.; Flow Cytometry:1 μg/ml.; Immunocytochemistry.; Functional application: Cytokine secretion studies.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: NK3.3 cells and KIR2DL4-Ig fusion protein
• Specificity: This Monoclonal antibody mAb#33 (also known as mAb 33 or 33) recognizes extracellular portion of CD158d / KIR2DL4, a 45 kDa NK cell marker. ; Cell surface expression and function of CD158d / KIR2DL4 depends on genotype of particular individuals.
• Buffer: Phosphate buffered saline (PBS), pH~7.4; State: Aff - Purified; State: Liquid purified IgG fraction (> 95% pure by SDS-PAGE); Preservative: 15 mM Sodium Azide
• Concentration: lot specific
• Purification: Protein-A Affinity Chromatography
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4
• Database Link:
  Q99706
• Background: CD158d / KIR2DL4 is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM, suggesting inhibitory function, but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells, but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-γ secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G.
• Synonyms: KIR103AS, G9P

Reference Data