AGR3 Mouse Monoclonal Antibody [Clone ID: AGR3.1]

SKU AM26017PU-N

AGR3 mouse monoclonal antibody, clone AGR3.1, Aff - Purified

Product Data

• Clone Name: AGR3.1
• Application: FC, IF, IHC, WB
• Recommended Dilution: Western blot: 1 μg/ml.; Positive Control: T47D breast cancer cell line.; Negative Control: H1299 lung carcinoma cell line.; Immunohistochemistry on Paraffin Sections: 1 μg/ml.; Positive Tissue: breast cancer.; Immunohistochemistry on Frozen Sections: 1 μg/ml.; Positive Tissue: breast cancer.; Immunocytochemistry: 1 μg/ml.; Positive Control: T47D breast cancer cell line.; Negative Control: H1299 lung carcinoma cell line.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified Human AGR3 protein.
• Specificity: This antibody recognizes the epitope HETTDKNLS within the AGR3 (AG3) protein (19-20 kDa), a secreted cytoplasmic protein which can serve as a marker of carcinogenesis.
• Buffer: PBS; State: Aff - Purified; State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE); Stabilizer: 0.2% (w/v) high-grade protease free BSA; Preservative: 15 mM Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: anterior gradient 3, protein disulphide isomerase family member
• Database Link:
  Q8TD06
• Background: AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG-3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.
• Synonyms: BCMP11, HAG3, HAG-3

Reference Data