Cd80 Hamster Monoclonal Antibody [Clone ID: 16-10A1]

SKU AM26002PU-N

Cd80 hamster monoclonal antibody, clone 16-10A1, Aff - Purified

Product Data

• Clone Name: 16-10A1
• Application: FC, FN, IHC, IP
• Recommended Dilution: Flow Cytometry: 6 μg/ml.; Immunoprecipitation.; Immunohistochemistry on Frozen Sections.; Functional Application: Blocking.
• Reactivity: Canine, Mouse
• Antibody Host: Hamster
• Isotype: IgG2
• Clonality: Monoclonal
• Immunogen: CD80-transfected CHO cell line
• Specificity: This Hamster antibody reacts with CD80 (B7-1), a 60 kDa single chain type I glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
• Buffer: Phosphate buffered saline (PBS), pH~7.4 with 15 mM Sodium Azide; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein-A affinity chromatography
• Conjugation: Unconjugated
• Storage: Store at 2-8°C for up to one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: CD80 antigen
• Database Link:
  Q00609
• Background: CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
• Synonyms: CD28LG, CD28LG1, LAB7, BB1, B7.1, B7-1

Reference Data