CD162 (SELPLG) Rat Monoclonal Antibody [Clone ID: HECA-452]
| Product Data | |
| Clone Name | HECA-452 |
|---|---|
| Application | FC, IHC |
| Recommended Dilution | Flow Cytometry. Immunohistochemistry on Paraffin Sections: 10 µg/ml. |
| Reactivity | Human, Mouse |
| Antibody Host | Rat |
| Isotype | IgM |
| Clonality | Monoclonal |
| Immunogen | SELPLG / PSGL-1 / CD162 antibody was raised against stromal preparation from human tonsils |
| Specificity | This antibody reacts to Selectin P Ligand (SELPLG). |
| Buffer | Phosphate-buffered solution, pH 7.2, 0.09% sodium azide State: Aff - Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Affinity chromatography |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | selectin P ligand |
| Database Link | |
| Background | SELPLG is the high affinity counter-receptor for P-selectin on myeloid cells and stimulated T lymphocytes. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. The organization of the SELPG gene closely resembles that of CD43 and the human platelet glycoprotein GpIb-alpha both of which have an intron in the 5-prime-noncoding region, a long second exon containing the complete coding region, and TATA-less promoters. |
| Synonyms | PSGL-1, Selectin P ligand, SELPLG |
| Reference Data | |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs) |
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