CD162 (SELPLG) Rat Monoclonal Antibody [Clone ID: HECA-452]

CAT#: AM20569PU-N

CD162 (SELPLG) rat monoclonal antibody, clone HECA-452, Aff - Purified

Product Images

IHC Image of AM20569PU-N: Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  IHC Image of AM20569PU-N: Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human peripheral blood lymphocytes stained with purified HECA-452, followed by anti-mouse IgG (AM20569PU-N) FITC

Specifications

Product Data

• Clone Name: HECA-452
• Applications: FC, IHC
• Recommended Dilution: Flow Cytometry.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
• Reactivities: Human, Mouse
• Host: Rat
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: SELPLG / PSGL-1 / CD162 antibody was raised against stromal preparation from human tonsils
• Specificity: This antibody reacts to Selectin P Ligand (SELPLG).
• Formulation: Phosphate-buffered solution, pH 7.2, 0.09% sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: selectin P ligand
• Database Link:
  Entrez Gene 20345 MouseEntrez Gene 6404 Human
  UniProt ID Q14242
• Background: SELPLG is the high affinity counter-receptor for P-selectin on myeloid cells and stimulated T lymphocytes. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. The organization of the SELPG gene closely resembles that of CD43 and the human platelet glycoprotein GpIb-alpha both of which have an intron in the 5-prime-noncoding region, a long second exon containing the complete coding region, and TATA-less promoters.
• Synonyms: PSGL-1, Selectin P ligand, SELPLG

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)