EVI2B Mouse Monoclonal Antibody [Clone ID: MEM-216]

SKU AM12138PU-N

EVI2B mouse monoclonal antibody, clone MEM-216, Aff - Purified

Product Data

• Clone Name: MEM-216
• Application: FC, IP
• Recommended Dilution: Flow cytometry.; Positive control: Raji, Daudi, HL-60 cells, peripheral blood lymphcocytes (strongly positive on CD19+ cells); Negative control: Jurkat, U-937 cells.; Immunoprecipitation.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Raji cells
• Specificity: This antibody detects CD361.
• Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4; State: Aff - Purified; State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A affinity chromatography
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: ecotropic viral integration site 2B
• Database Link:
  P34910
• Background: CD361, also known as EVI2B (Ecotropic Viral Integration site 2B) or EVDB, is a poorly characterized type I transmembrane protein, expressed from one of three genes embedded in intron 27b of the neurofibromatosis type 1 (NF1) gene. The DNA strand that is transcribed to produce CD361 is the complementary one to the strand encoding NF1. Murine homolog to human CD361 is associated with ecotropic viral insertions, which have been implicated in the expression of murine myeloid leukemias. CD361 has been also reported to be involved in melanocyte and keratinocyte differentiation. However, it is expressed mainly in peripheral blood and bone marrow.
• Synonyms: EVDB

Reference Data