SOD2 Mouse Monoclonal Antibody [Clone ID: 37CT127.5.11.6]
Product Data | |
Clone Name | 37CT127.5.11.6 |
---|---|
Application | IHC, WB |
Recommended Dilution | ELISA: 1/4000. Western blotting: 1/2000. Immunohistochemistry on Paraffin Sections: 1/10-1/50. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified His-tagged SOD protein (Fragment). |
Specificity | This antibody is specific to SOD2. |
Buffer | PBS containing 0.09% (W/V) Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Purification | Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 24722 Da (Calculated) |
Gene Name | superoxide dismutase 2, mitochondrial |
Database Link | |
Background | SOD2 is a member of the iron/manganese superoxide dismutase family. It is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. |
Synonyms | Superoxide dismutase Mn |
Reference Data |
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