SYBL1 (VAMP7) Mouse Monoclonal Antibody [Clone ID: 158.2]
Product Data | |
Clone Name | 158.2 |
---|---|
Application | ELISA, FC, IF, IHC, WB |
Recommended Dilution | ELISA. Western Blot: 1/500-1/2000. Immunofluorescence. Immunohistochemistry: 1/10-1/400. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | GST-TI-VAMP recombinant protein |
Specificity | Reacts with Human 25 kDa TI-VAMP protein. Cross reacts with TI-VAMP from different species (Mouse, Rat, Canine). |
Buffer | 0.1M Tris, 0.1M Glycine, 2% Sucrose State: Purified State: Lyophilized purified powder Preservative: None |
Reconstitution Method | Restore in distilled water. |
Concentration | 1.0 mg/ml after reconstitution |
Purification | Affinity Chromatography on Protein A |
Conjugation | Unconjugated |
Storage | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Ambient |
Gene Name | vesicle associated membrane protein 7 |
Database Link | |
Background | SYBL1 (Synaptobrevin-like 1) is found ubiquitously and is an unusual v-SNAREs molecule implicated in cellular exocytosis. The SYBL1 gene is found on the pseudoautosomal region (PAR) of X chromosome. It is a highly conserved gene and has been shown to be silenced on inactive X and Y chromosomes. In ICF syndrome, a human disease affecting DNA methylation, SYBL1 escapes from silencing and this correlates with the observed altered patterns of histone methylation and acetylation found. An association between some SYBL1 alleles and bipolar affective disorder (BPAD) has been observed. |
Synonyms | VAMP7, Ti-VAMP, Vesicle-associated membrane protein 7 |
Reference Data |
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