Myoferlin (MYOF) Mouse Monoclonal Antibody [Clone ID: 7D2]

CAT#: AM10201PU-N

Myoferlin (MYOF) mouse monoclonal antibody, clone 7D2, Purified

Product Images

Detection of Myoferlin in differents cells using Myoferlin antibody Cat.-No AM10201PU-N. Lane 1: C2Cl2 cell lysate. Lane 2: Fibroblast cell lysate.

Specifications

Product Data

• Clone Name: 7D2
• Applications: ELISA, IHC, WB
• Recommended Dilution:

  ELISA.
  Western Blot: 1/50-1/5000.
  Immunohistochemistry: 1/20-1/1000.

• Reactivities: Human, Mouse
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Synthetic peptide derived from N-term domain of the Human FER1L3 protein.
• Specificity: This antibody reacts with Human 234 kDa FER1L3 protein.
  Cross reacts with Mouse protein.
• Formulation: 0.1M Tris, 0.1M Glycine, 2% Sucrose
  State: Purified
  State: Lyophilized purified antibody
  Preservative: None
• Reconstitution Method: Restore in distilled water
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: myoferlin
• Database Link:
  Entrez Gene 26509 Human
  UniProt ID Q9NZM1
• Background: Myoferlin belongs to the ferlin family and contains five C2 domains. It is a calcium/phospholipid binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. It is also involved in endocytic recycling and implicated in VEGF signal transduction by regulating the levels of the receptor KDR. Myoferlin is expressed in myoblast and endothelial cells (at protein level), highly expressed in cardiac and skeletal muscles, also present in lung and at very low levels in kidney, placenta and brain. There are eight named isoforms.
• Synonyms: MYOF, FER1L3, KIAA1207