CLEC4E Mouse Monoclonal Antibody [Clone ID: AT16E3]

SKU AM09361PU-N

CLEC4E mouse monoclonal antibody, clone AT16E3, Purified

Product Data

• Clone Name: AT16E3
• Application: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA.; Western blot: 1/250-1/1000.; Immunofluorescence: 1/250-1/500.; Immunohistochemistry on Paraffin Embedded tissues: 1/50.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Recombinant Human MINCLE (41-219aa) purified from E. coli
• Specificity: The antibody recognizes Human CLEC4E (MINCLE). Other species not tested.
• Buffer: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol; State: Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein-G Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: C-type lectin domain family 4 member E
• Database Link:
  Q9ULY5
• Background: MINCLE (macrophage inducible C-type lectin, also called CLEC4E or CLECSF9), which is a diverse family of protein which was originally defined by their ability to recognize a wide range of ligand of carbohydrate structure. MINCLE expressed in macrophages subjected to several types of stress. It plays an essential role in response to trehalose-6,6'-dimycolate (TDM) and activated by a synthetic analogue, trehalose dibehenate (TDB). Recently it was reported that MINCLE is associated with an immunoreceptor tyrosine-based activation motif–containing Fc receptor γ chain (FcRγ) and functions as an activating receptor for damaged self- and non–self-pathogenic fungi.
• Synonyms: CLECSF9, MINCLE

Reference Data

• Protein Families: Druggable Genome, Transmembrane