Plakophilin 4 (PKP4) (85-104) Mouse Monoclonal Antibody [Clone ID: 7.7.9 (p0071-1)]

SKU AM09132SU-N

Plakophilin 4 (PKP4) (85-104) mouse monoclonal antibody, clone 7.7.9 (p0071-1), Supernatant

Product Data

• Clone Name: 7.7.9 (p0071-1)
• Application: IF, IHC, WB
• Recommended Dilution: Immunoblotting: 1/10-1/50.; Immunofluorescence: Undiluted.; Immunohistochemistry on Frozen Sections: Undiluted.; Immunohistochemistry on Paraffin Sections:; Incubation Time: 1-1.5 h at RT. ; Positive Control: MCF-7 cells.
• Reactivity: Bovine, Human, Mouse
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic peptide of human p0071 (aa position 85-104: EKSFPWRSTDVNTGVSKPR)
• Specificity: This antibody recognizes Plakophilin-4. ; Detects a plaque protein (p0071) specific for a subtype of adherens junctions, with a molecular mass of 135 kD and is closely related to neurojungin / delta-catenin and ARVC (all belonging to the p120 armadillo subfamily). p0071 is specifically detected in the plaques of the composite junctions (area compositae) of cardiac intercalated disks, in puncta adhaerentia of single- and multi-layered epithelia and blood vessel endothelial cells.; it is, however, absent from desmosomes. This protein was also described as plakophilin 4.; Tested Reactivities on Cultured Cell Lines:MCF-7, A431, CaCo-2, HT-29, PLC, 16HBE14o, HaCaT, SV80,; U333 CG, 3T3, RVF-SMC, MH1C1.
• Buffer: State: Supernatant; State: Liquid Hybridoma Culture Supernatant; Preservative: 0.09% Sodium Azide
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: plakophilin 4
• Database Link:
  Q99569
• Background: Plakophilin 4 (PKP4) is an Armadillo-like protein, characterized by a series of armadillo repeats. It is a component of desmosomal plaques and may play a role in junctional plaque organization.
• Synonyms: PKP4, p0071

Reference Data