CRABP1 Mouse Monoclonal Antibody [Clone ID: AT1A1]

CAT#: AM09092PU-S

CRABP1 mouse monoclonal antibody, clone AT1A1, Purified

Product Images

Western blot analysis : The extracts of mouse eye (30 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human CRABP1 antibody (1/500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

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  Immunohistochemistry: -N CRABP1 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Skeletal Muscle followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Immunohistochemistry: -N CRABP1 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Prostate followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Immunohistochemistry: -N CRABP1 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Thyroid followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Clone Name: AT1A1
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Western blot: 1/500-1/1,000.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
• Reactivities: Human, Mouse
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Recombinant Human CRABP1 (1-137 aa) purified from E. coli
• Specificity: The antibody recognizes Human and Mouse CRABP1. Other species not tested.
• Formulation: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
  State: Purified
  State: Liquid purified IgG fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: cellular retinoic acid binding protein 1
• Database Link:
  Entrez Gene 12903 MouseEntrez Gene 1381 Human
  UniProt ID P29762
• Background: CRABP1 (cellular retinoic acid-binding protein 1) is a member of specific carrier proteins for members of the vitamin A family. CRABP1 is assumed to play an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid. It is constitutively expressed and is believed to have different functions in the cell than the related CRABP2. Interestingly, Sytenol A bakuchiol has very specific receptor specificity over retinol and has no effect on the RAR-beta and RAR-gamma receptors and down-regulates CRABP1.
• Synonyms: CRABP-I, RBP5