BRCC36 (BRCC3) Mouse Monoclonal Antibody [Clone ID: AT3B1]

SKU AM09089PU-N

BRCC36 (BRCC3) mouse monoclonal antibody, clone AT3B1, Purified

Product Data

• Clone Name: AT3B1
• Application: ELISA, IHC, WB
• Recommended Dilution: ELISA.; Western blot (1:1,000 - 1:2,000).; Immunohistochemistry on Paraffin Sections: (5 µg/ml).
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant BRCC36 (1-316 aa) purified from E. coli
• Specificity: The antibody recognizes human BRCC3 / BRCC36. Other species not tested.
• Buffer: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol; State: Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein-G affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: BRCA1/BRCA2-containing complex subunit 3
• Database Link:
  P46736
• Background: BRCC3 (BRCC36, BRCA1/BRCA2-containing complex, subunit 36) is a holoenzyme complex containing BRCA1, BRCA2. BRCC36 is an ubiquitin E3 ligase complex that has a role in DNA repair and enhances cellular survival following DNA damage. This protein is also thought to be involved in the cellular response to ionizing radiation and progression through the G2/M checkpoint.
• Synonyms: BRCC36, C6.1A, CXorf53

Reference Data

• Protein Families: Druggable Genome, Protease