Cyclophilin F (PPIF) Mouse Monoclonal Antibody [Clone ID: AT1F5]
Product Data | |
Clone Name | AT1F5 |
---|---|
Application | ELISA, FC, IF, IHC, WB |
Recommended Dilution | ELISA. Western blot: 1/500 - 1/1000. Flow Cytometry. Immunohistochemistry on Paraffin sections: 1/50-1/100. Immunofluorescence/Immnunocytochemistry. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Recombinant human PPIF (30-207 aa) purified from E. coli |
Specificity | The antibody recognizes PPIF. |
Buffer | PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Protein-G affinity chromatography |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | peptidylprolyl isomerase F |
Database Link | |
Background | Cyclophilin F (also known as Peptidylprolyl isomerase F, PPIF) is a member of peptidyl-prolyl cis-transisomerase family. They are highly-conserved cytoplasmic enzymes that accelerate protein folding. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. |
Synonyms | PPIase F, Rotamase F, PPIF, CYP3 |
Reference Data |
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