TREM2 Mouse Monoclonal Antibody [Clone ID: 2B5]
Product Data | |
Clone Name | 2B5 |
---|---|
Application | ELISA, WB |
Recommended Dilution | ELISA. Western blot (1/500-1/1,000). |
Reactivity | Human, Mouse |
Antibody Host | Mouse |
Isotype | IgG3 |
Clonality | Monoclonal |
Immunogen | Recombinant Human TREM2 (19-161 aa) purified from E. coli |
Specificity | The antibody recognizes Human and Mouse TREM2. Other species not tested. |
Buffer | PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified IgG fraction |
Concentration | lot specific |
Purification | Protein-G Affinity Chromatography |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | triggering receptor expressed on myeloid cells 2 |
Database Link | |
Background | The triggering receptor expressed on myeloid cells-2 (TREM2) is a membrane protein that interacts with the TYROBP protein. The TREM2 and TYROBP proteins form a complex that transmits chemical signals to activate the cell. This complex is involved in the growth and development of several types of immune cells, particularly dendritic cells and activates these cells, triggering an inflammatory response to injury or disease. And the TYROBP-TREM2 complex also activates cells in the skeletal system and in the brain and spinal cord (central nervous system). |
Synonyms | TREM-2, Trem2a, Trem2b, Trem2c |
Reference Data |
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