alpha Synuclein (SNCA) (also beta reactive) Mouse Monoclonal Antibody [Clone ID: 3B6]

SKU AM09033PU-N

alpha Synuclein (SNCA) (also beta reactive) mouse monoclonal antibody, clone 3B6, Purified

Product Data

• Clone Name: 3B6
• Application: ELISA, FC, IF, WB
• Recommended Dilution: ELISA.; Western blot (1/1,000-1/2,000). ; Flow Cytometry.; Immunofluorescence.
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human α-synuclein (119-140aa) purified from E. coli
• Specificity: The antibody recognizes α,β - Synuclein.
• Buffer: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol; State: Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein-G affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: synuclein alpha
• Database Link:
  P37840
• Background: α-synuclein (amino acids 119-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. α-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Specially, the non-Aβ component of amyloid plaques is a highly amyloidogenic peptide consisting of 35 amino acids which was first identified associated with senile plaques in the Alzheimer's disease brain.
• Synonyms: NACP, PARK1

Reference Data