PGP9.5 (UCHL1) Mouse Monoclonal Antibody [Clone ID: 3D9]
Product Data | |
Clone Name | 3D9 |
---|---|
Application | ELISA, IF, IHC, WB |
Recommended Dilution | ELISA. Western blot: 1/1,000-1/2,000. Flow Cytometry. Immunofluorescence/Immnunocytochemistry. Immunohistochemistry on Paraffin Sections: 1/100-1/200. |
Reactivity | Human, Mouse |
Antibody Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Recombinant human PGP9.5 (1-223 aa) purified from E. coli |
Specificity | The antibody recognizes Human and Mouse PGP9.5. Other species not tested. |
Buffer | PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein G |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | ubiquitin C-terminal hydrolase L1 |
Database Link | |
Background | PGP9.5/UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. PGP9.5 is a component of the ubiquitin system, which has a fundamental role in regulating various biological activities. PGP9.5 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility. |
Synonyms | UCH-L1, PGP 9.5, Ubiquitin thioesterase L1, Neuron cytoplasmic protein 9.5 |
Reference Data |
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