Phosphoserine phosphatase (PSPH) Mouse Monoclonal Antibody [Clone ID: 3G12]

SKU AM09015PU-N

Phosphoserine phosphatase (PSPH) mouse monoclonal antibody, clone 3G12, Purified

Product Data

• Clone Name: 3G12
• Application: ELISA, IHC, WB
• Recommended Dilution: ELISA.; Western blot (1/1,000-1/2,000); Recommended Starting Dilution: 1/1,000.; Immunohistochemistry on Paraffin Sections (10 µg/ml).
• Reactivity: Human, Mouse
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human PSP (1-225 aa) purified from E. coli
• Specificity: The antibody recognizes Phosphoserine Phosphatase.
• Buffer: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol; State: Purified; State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Protein-A affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: phosphoserine phosphatase
• Database Link:
  P78330
• Background: Human phosphoserine phosphatase (HPSP), specific for D- and L- phosphoserine, has been identified in all human tissues. HPSP is a Mg(2+)-dependent phosphoserine phosphatase. The three dimensional structure of HPSP reveals the structural and functional role of the divalent cation in the active site of phosphatases. In particular, the complex structures reveal that the open-closed environmental change of the active site, generated by local rearrangement of the alpha-helical bundle domain, is important for the substrate recognition and hydrolysis.
• Synonyms: PSPH, PSPase, PSP, EC=3.1.3.3, O-phosphoserine phosphohydrolase, L-3-phosphoserine phosphatase

Reference Data