FADD Mouse Monoclonal Antibody [Clone ID: J1D2]
Product Data | |
Clone Name | J1D2 |
---|---|
Application | ELISA, IHC, WB |
Recommended Dilution | ELISA. Western blot (1:500 - 1,000). Immunohistochemistry on paraffin sections (1:50 - 1:100). |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Recombinant human FADD (1-208 aa) purified from E. coli |
Specificity | The antibody recognizes human FADD. Other species not tested. |
Buffer | PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein-G affinity chromatography |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Gene Name | Fas associated via death domain |
Database Link | |
Background | FADD (Fas-associated protein with death domain) is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. This protein is implicated in survival/proliferation and cell cycle progression. FADD functions are also regulated via cellular sublocalization, protein phosphorylation, and inhibitory molecules. |
Synonyms | FAS-associated death domain protein, MORT1, GIG3 |
Reference Data |
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