Itgb7 Rat Monoclonal Antibody [Clone ID: DATK32]

SKU AM08074PU-N

Itgb7 rat monoclonal antibody, clone DATK32, Purified

Product Data

• Clone Name: DATK32
• Application: FC, FN, IHC
• Recommended Dilution: Flow Cytometry: ≤ 1 µg/10⁶ cells. (Ref.1-4); Immunohistochemistry on Frozen Sections. (Ref.3); Induction of homotypic cellular aggregation. (Ref.1); Blockade of binding to cell adhesion molecules. (Ref.1)
• Reactivity: Mouse
• Antibody Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: AKR/Cum mouse spontaneous T lymphoma cell line TK1. (Ref.1)
• Specificity: This antibody is specific to mouse LPAM1 (Integrin alpha 4 beta 7).; It recognises a conformational epitope on the heterodimer.
• Buffer: 100 mM Borate Buffered Saline, pH 8.2.; No preservatives or amine-containing buffer salts added.; State: Purified; State: Liquid purified Ig fraction.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: integrin beta 7
• Database Link:
  P26011
• Background: The lymphocyte Peyer’s patch adhesion molecule (LPAM-1), also known as Integrin alpha 4 beta 7 is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (Ref.1-4)
• Synonyms: Integrin beta-P, M290 IEL antigen, ITGB7, LPAM-1, LPAM1

Reference Data