Cd28 Hamster Monoclonal Antibody [Clone ID: 37.51]

CAT#: AM08037PU-N

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Cd28 hamster monoclonal antibody, clone 37.51, Purified

Conjugation: Unconjugated Biotin FITC



USD 376.00

3 Days*

Size
    • 500 ug

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Specifications

Product Data
Clone Name 37.51
Applications FC, FN, IP
Recommended Dilution Flow Cytometry (Ref.1,2).
Immunoprecipitation (Ref.1).
Functional Assay: In vitro costimulation of T cells and NK cells (Ref.1-3,7-9,11).
Reactivities Mouse
Host Hamster
Isotype IgG2
Clonality Monoclonal
Immunogen C57BL/6N mouse T cell lymphoma EL-4 cell line.
Specificity This antibody is specific to CD28 costimulatory receptor (Mr. 40 kDa)
Formulation Borate Buffered Saline, pH 8.2.
No preservatives or amine-containing buffer salts added.
State: Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name CD28 antigen
Background CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. (Ref.1-4)
CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses. (Ref.5-8)
Synonyms TP44
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.