c Fos (FOS) Mouse Monoclonal Antibody [Clone ID: 2G2]
Product Data | |
Clone Name | 2G2 |
---|---|
Application | ELISA, FC, IHC, WB |
Recommended Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Flow Cytometry: 1/200 - 1/400. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of Human FOS expressed in E. Coli. |
Specificity | Recognizes c-fos |
Buffer | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 40.7 kDa |
Gene Name | Fos proto-oncogene, AP-1 transcription factor subunit |
Database Link | |
Background | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. |
Synonyms | FOS, G0S7 |
Reference Data |
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