MCP1 (CCL2) Mouse Monoclonal Antibody [Clone ID: 2D8]

SKU AM06749PU-N

MCP1 (CCL2) mouse monoclonal antibody, clone 2D8, Purified

Product Data

• Clone Name: 2D8
• Application: ELISA, FC, IF, IHC, WB
• Recommended Dilution: ELISA: 1/10000.; Western Blot: 1/500-1/2000.; Immunofluorescence: 1/200-1/1000.; Flow Cytometry: 1/200-1/400.; Immunohistochemistry on Paraffin Sections: 1/200-1/1000.
• Reactivity: Human, Monkey, Mouse
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of Human CCL2 expressed in E.Coli.
• Specificity: Recognizes CCL2
• Buffer: PBS; State: Purified; State: Liquid purified antibody; Stabilizer: 0.5% protein stabilizer; Preservative: 0.05% Sodium Azide
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. ; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: 11 kDa
• Gene Name: C-C motif chemokine ligand 2
• Database Link:
  P13500
• Background: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
• Synonyms: C-C motif chemokine 2, SCYA2, MCAF, Small-inducible cytokine A2, MCP-1, HC11, HC-11

Reference Data