CD95 (FAS) Mouse Monoclonal Antibody [Clone ID: 4F8H6]
| Product Data | |
| Clone Name | 4F8H6 |
|---|---|
| Application | ELISA, FC, IF, WB |
| Recommended Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow Cytometry: 1/200 - 1/400. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of Human FAS expressed in E. Coli. |
| Specificity | Recognizes CD95 / FAS |
| Buffer | PBS State: Purified State: Liquid purified antibody Stabilizer: 0.5% protein stabilizer Preservative: 0.05% Sodium Azide |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 37.7 kDa |
| Gene Name | Fas cell surface death receptor |
| Database Link | |
| Background | Fas (APO-1, CD95) is a 45 kDa cell surface protein that mediates apoptosis when crosslinked with agonistic anti-Fas antibodies or Fas ligand (FasL). FasL is a tumor necrosis factor (TNF)-related type II membrane protein and is expressed in various tissue and cells. Both Fas and FasL are thought to play an important role in the apoptosis processes that takes place during T cell development. |
| Synonyms | FASLG receptor, Apo-1 antigen, APT1, FAS1, TNFRSF6 |
| Reference Data | |
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