RPS6KA3 Mouse Monoclonal Antibody [Clone ID: 4E10]
Product Data | |
Clone Name | 4E10 |
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Application | ELISA, FC, IF, WB |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of human RSK2 expressed in E. Coli. |
Specificity | This antibody reacts to RSK2. |
Buffer | State: Ascites State: Ascitic fluid containing 0.03% sodium azide. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 80 kDa |
Gene Name | ribosomal protein S6 kinase A3 |
Database Link | |
Background | This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). |
Synonyms | RSK-2, ISPK1, ISPK-1, MAPKAPK1, MAPKAPK-1b, S6K-alpha-3, p90RSK3, Ribosomal S6 kinase 2 |
Reference Data |
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