gamma Catenin (JUP) Mouse Monoclonal Antibody [Clone ID: 4C12]
Product Data | |
Clone Name | 4C12 |
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Application | ELISA, IF, IHC, WB |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry on paraffin sections: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of human JUP expressed in E. Coli. |
Specificity | This antibody reacts to JUP. |
Buffer | State: Ascites State: Ascitic fluid containing 0.03% sodium azide. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 82 kDa |
Gene Name | junction plakoglobin |
Database Link | |
Background | This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. |
Synonyms | Desmoplakin-3, Desmoplakin III, Catenin gamma, JUP, CTNNG, DP3 |
Reference Data |
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