Ku80 (XRCC5) Mouse Monoclonal Antibody [Clone ID: 5C5]

SKU AM06649SU-N

Ku80 (XRCC5) mouse monoclonal antibody, clone 5C5, Ascites

Product Data

• Clone Name: 5C5
• Application: ELISA, FC, IF, IHC, WB
• Recommended Dilution: Western Blot: 1/500 - 1/2000.; Immunohistochemistry on paraffin sections: 1/200 - 1/1000.; Immunofluorescence: 1/200 - 1/1000.; Flow cytometry: 1/200 - 1/400.; ELISA: 1/10000.
• Reactivity: Human, Mouse
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of human XRCC5 expressed in E. Coli.
• Specificity: This antibody reacts to XRCC5.
• Buffer: State: Ascites; State: Ascitic fluid containing 0.03% sodium azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 86 kDa
• Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 5
• Database Link:
  P13010
• Background: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
• Synonyms: TLAA, G22P2, CTCBF, CTC85

Reference Data