alpha smooth muscle Actin (ACTA2) Mouse Monoclonal Antibody [Clone ID: 4A4]
Product Data | |
Clone Name | 4A4 |
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Application | ELISA, FC, IF, IHC, WB |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry on paraffin sections: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. |
Reactivity | Human, Monkey, Mouse, Rat |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Synthesized peptide of human ACTA2. |
Specificity | This antibody reacts to ACTA2. |
Buffer | State: Ascites State: Ascitic fluid containing 0.03% sodium azide. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 42 kDa |
Gene Name | actin, alpha 2, smooth muscle, aorta |
Database Link | |
Background | The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Synonyms | ACTSA, ACTVS, Alpha-actin-2 |
Reference Data |
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