NFKB1 Mouse Monoclonal Antibody [Clone ID: 5D10D11]

SKU AM06646SU-N

NFKB1 mouse monoclonal antibody, clone 5D10D11, Ascites

Product Data

• Clone Name: 5D10D11
• Application: ELISA, FC, IF, IHC, WB
• Recommended Dilution: Western Blot: 1/500 - 1/2000.; Immunohistochemistry on paraffin sections: 1/200 - 1/1000.; Immunofluorescence: 1/200 - 1/1000.; Flow cytometry: 1/200 - 1/400.; ELISA: 1/10000.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of human NFKB1 expressed in E. Coli.
• Specificity: This antibody reacts to NFKB1.
• Buffer: State: Ascites; State: Ascitic fluid containing 0.03% sodium azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 50 kDa/105 kDa
• Gene Name: nuclear factor kappa B subunit 1
• Database Link:
  P19838
• Background: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.
• Synonyms: NFKB1, KBF1, EBP-1, EBP1, NF-kappa-B p50

Reference Data