GRK2 Mouse Monoclonal Antibody [Clone ID: 3F8]

SKU AM06612SU-N

GRK2 mouse monoclonal antibody, clone 3F8, Ascites

Product Data

• Clone Name: 3F8
• Application: ELISA, IF, IHC, WB
• Recommended Dilution: Western Bloting: 1/500 - 1/2000.; Immunohistochemistry on paraffin sections: 1/200 - 1/1000.; Immunofluorescence: 1/200 - 1/1000.; ELISA: 1/10000.
• Reactivity: Human, Monkey, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of human GRK2 expressed in E. Coli.
• Specificity: This antibody reacts to GRK2.
• Buffer: State: Ascites; State: Ascitic fluid containing 0.03% sodium azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 80 kDa
• Gene Name: G protein-coupled receptor kinase 2
• Database Link:
  P25098
• Background: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes
• Synonyms: BARK, BARK1, GRK2, Beta-adrenergic receptor kinase 1

Reference Data