SMAD4 Mouse Monoclonal Antibody [Clone ID: 4G1C6]

SKU AM06501SU-N

SMAD4 mouse monoclonal antibody, clone 4G1C6, Ascites

Product Data

• Clone Name: 4G1C6
• Application: ELISA, FC, IF, IHC, WB
• Recommended Dilution: ELISA: 1/10000.; Western Blot: 1/500 - 1/2000.; Flow Cytometry: 1/200 - 1/400. ; Immunofluorescence: 1/200 - 1/1000. ; Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of Human SMAD4 expressed in E. Coli.
• Specificity: Recognizes SMAD4
• Buffer: State: Ascites; State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. ; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: 65 kDa
• Gene Name: SMAD family member 4
• Database Link:
  Q13485
• Background: Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily; SMAD4 is the common SMAD (co-SMAD). Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. May act as a tumor suppressor。Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome.
• Synonyms: SMAD family member 4, SMAD-4, SMAD 4, MADH4, MAD homolog 4, DPC4

Reference Data