Plzf (ZBTB16) Mouse Monoclonal Antibody [Clone ID: 5B3]

CAT#: AM06484SU-N

Plzf (ZBTB16) mouse monoclonal antibody, clone 5B3, Ascites

Product Images

Western blot analysis using ZBTB16 mouse mAb against Hela (1) cell lysate.

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  Immunofluorescence analysis of Hela cells using ZBTB16 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Specifications

Product Data

• Clone Name: 5B3
• Applications: ELISA, IF, WB
• Recommended Dilution: Western Blot: 1/500 - 1/2000.
  Immunofluorescence: 1/200 - 1/1000.
  ELISA: 1/10000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of human ZBTB16 expressed in E. Coli.
  
• Specificity: This antibody reacts to ZBTB16.
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% sodium azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 74 kDa
• Gene Name: zinc finger and BTB domain containing 16
• Database Link:
  Entrez Gene 7704 Human
  UniProt ID Q05516
• Background: This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. Tissue specificity: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.
• Synonyms: PLZF, ZNF145