TCF3 / E2A (TCF3) Mouse Monoclonal Antibody [Clone ID: 6B8]
| Product Data | |
| Clone Name | 6B8 |
|---|---|
| Application | ELISA, FC, WB |
| Recommended Dilution | ELISA: 1/10000. Western Bloting: 1/500 - 1/2000. Flow Cytometry: 1/200 - 1/400. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of human TCF3 expressed in E. Coli. |
| Specificity | Recognizes TCF3 |
| Buffer | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 67.6 kDa |
| Gene Name | transcription factor 3 |
| Database Link | |
| Background | Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. |
| Synonyms | Transcription factor 3, TCF-3, Transcription factor E2-alpha, ITF1, ITF-1 |
| Reference Data | |
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