FABP2 Mouse Monoclonal Antibody [Clone ID: 9A9B7B3]

CAT#: AM06397SU-N

FABP2 mouse monoclonal antibody, clone 9A9B7B3, Ascites

Product Images

Western blot analysis using FABP2 mouse mAb against FABP2-hIgGFc transfected HEK293 (1) cell lysate and LOVO (2) cell lysate.

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  Immunohistochemical analysis of paraffin-embedded human Small Intestine tissues using FABP2 mouse mAb

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  Immunofluorescence analysis of 3T3-L1 cells using FABP2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

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  Flow cytometric analysis of LOVO cells using FABP2 mouse mAb (green) and negative control (purple).

Specifications

Product Data

• Clone Name: 9A9B7B3
• Applications: ELISA, FC, IF, IHC, WB
• Recommended Dilution: Western Blot: 1/500 - 1/2000.
  Immunohistochemistry on paraffin sections: 1/200 - 1/1000.
  Immunofluorescence: 1/200 - 1/1000.
  Flow cytometry: 1/200 - 1/400.
  ELISA: 1/10000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of human FABP2 expressed in E. Coli.
• Specificity: This antibody reacts to FABP2.
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% sodium azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 15 kDa
• Gene Name: fatty acid binding protein 2
• Database Link:
  Entrez Gene 2169 Human
  UniProt ID P12104
• Background: The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. Genetic variation in FABP2 may thus contribute to interindividual variation in the response of plasma lipoproteins to different dietary fibres, but the mechanism does not appear to be related to increases in fecal bile acid secretion.
• Synonyms: FABP-2, Fatty acid-binding protein, intestinal, I-FABP, FABPI