PAK2 Mouse Monoclonal Antibody [Clone ID: 3B5]

SKU AM06347SU-N

PAK2 mouse monoclonal antibody, clone 3B5, Ascites

Product Data

• Clone Name: 3B5
• Application: IF, IHC, WB
• Recommended Dilution: ELISA: 1/10000. ; Western Bloting: 1/500 - 1/2000.; Immunofluorescence: 1/200 - 1/1000. ; Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
• Reactivity: Human, Monkey
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of PAK2 expressed in E. Coli.
• Specificity: Recognizes PAK2
• Buffer: State: Ascites; State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 61 kDa
• Gene Name: p21 (RAC1) activated kinase 2
• Database Link:
  Q13177
• Background: PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.
• Synonyms: PAK 2, PAK-2, Gamma-PAK, PAK gamma, PAK65, p21-activated kinase 2, p58

Reference Data