FMRP (FMR1) Mouse Monoclonal Antibody [Clone ID: 4G9]
Product Data | |
Clone Name | 4G9 |
---|---|
Application | IF, IHC, WB |
Recommended Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of human FMR1 expressed in E. Coli. |
Specificity | Recognizes FMR1 also known as POF, FMRP, FRAXA. |
Buffer | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 71 kDa |
Gene Name | fragile X mental retardation 1 |
Database Link | |
Background | FMR1, also known as POF, FMRP, FRAXA. Entrez Protein is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. |
Synonyms | Fragile X mental retardation 1 protein, Protein FMR-1 |
Reference Data |
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