Lysyl tRNA synthetase (KARS) Mouse Monoclonal Antibody [Clone ID: 8G12C1]
| Product Data | |
| Clone Name | 8G12C1 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | ELISA: 1/10000. Western blot: 1/500 - 1/2000. Immunohistochemistry on Paraffin Sections: 1/200-1/1000. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of KARS(aa90-174) expressed in E. Coli. |
| Specificity | Recognizes Lysyl Trna Synthetase (KARS). |
| Buffer | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | lysyl-tRNA synthetase |
| Database Link | |
| Background | Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. |
| Synonyms | Lysyl-tRNA synthetase, KIAA0070, LysRS, Lysine-tRNA ligase |
| Reference Data | |
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