SND1 Mouse Monoclonal Antibody [Clone ID: 2D7]
| Product Data | |
| Clone Name | 2D7 |
|---|---|
| Application | WB |
| Recommended Dilution | ELISA: 1/10000. Western Blotting: 1/500 - 1/2000. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of SND1 (aa361-485) expressed in E. Coli. |
| Specificity | Recognizes SND1/P100 |
| Buffer | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 102 kDa |
| Gene Name | staphylococcal nuclease and tudor domain containing 1 |
| Database Link | |
| Background | SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, it functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activatior of EBNA-2. It also interacts with EAV, NSP1,GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP. |
| Synonyms | TDRD11 |
| Reference Data | |
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