Fibulin 5 (FBLN5) Mouse Monoclonal Antibody [Clone ID: 1G6A4]
| Product Data | |
| Clone Name | 1G6A4 |
|---|---|
| Application | ELISA, IHC, WB |
| Recommended Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunohistochemistry o Paraffin Sections: 1/200 - 1/1000. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Purified recombinant fragment of FBLN5 (aa242-448) expressed in E. Coli. |
| Specificity | Recognizes Fibulin-5 |
| Buffer | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | fibulin 5 |
| Database Link | |
| Background | The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. |
| Synonyms | FIBL-5, FBLN5, DANCE, Urine p50 protein, UP50 |
| Reference Data | |
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