GST3 (GSTP1) Mouse Monoclonal Antibody [Clone ID: 3F2C2]

SKU AM06145SU-N

GST3 (GSTP1) mouse monoclonal antibody, clone 3F2C2, Ascites

Product Data

• Clone Name: 3F2C2
• Application: ELISA, FC, IF, IHC, WB
• Recommended Dilution: ELISA: 1/10000. ; Western Blot: 1/500-1/2000.; Immunofluorescence: 1/200-1/1000.; Flow Cytometry: 1/200-1/400. ; Immunohistochemistry on Paraffin Sections: 1/200-1/1000.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of Human GSTP1 expressed in E. Coli.
• Specificity: Recognizes GSTP1 (glutathione-S-transferase, pi 1).
• Buffer: State: Ascites; State: Ascitic fluid; Preservative: 0.03% Sodium Azide
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: 23 kDa
• Gene Name: glutathione S-transferase pi 1
• Database Link:
  P09211
• Background: GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90%) of prostate carcinomas and is associated with transcriptional down-regulation.
• Synonyms: Glutathione S-transferase P, GSTP1-1, GST pi, GST class-pi, FAEES3

Reference Data