CIB1 Mouse Monoclonal Antibody [Clone ID: 5A1F5E12]

SKU AM06136SU-N

CIB1 mouse monoclonal antibody, clone 5A1F5E12, Ascites

Product Data

• Clone Name: 5A1F5E12
• Application: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/10000.; Western Blot: 1/500 - 1/2000.; Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of CIB1 expressed in E. Coli.
• Buffer: State: Ascites; State: Ascitic fluid; Preservative: 0.03% Sodium Azide
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. ; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: calcium and integrin binding 1
• Database Link:
  Q99828
• Background: CIB1 (also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.
• Synonyms: Calmyrin, KIP, PRKDCIP, SIP2-28, CIBP

Reference Data