gamma Synuclein (SNCG) Mouse Monoclonal Antibody [Clone ID: 1H10D2]

CAT#: AM06134PU-N

gamma Synuclein (SNCG) mouse monoclonal antibody, clone 1H10D2, Purified

Product Images

Western blot analysis using SNCG antibody Cat.-No AM06134PU-N against truncated SNCG recombinant protein.

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  Immunohistochemical analysis of paraffin-embedded human ovary carcinoma (left) and breast carcinoma (right), showing cytoplasmic (ovary carcinoma) localization, cytoplasmic and nuclear (breast carcinoma) localization using SNCG antibody Cat.-No AM06134PU-N with DAB staining.

Specifications

Product Data

• Clone Name: 1H10D2
• Applications: IHC, WB
• Recommended Dilution: Western Blot: 1/500 - 1/2000.
  Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
  ELISA: 1/10000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of SNCG expressed in E. Coli.
• Specificity: Recognizes SNCG (breast cancer-specific protein 1).
• Formulation: Ascitic fluid containing 0.03% sodium azide.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: synuclein gamma
• Database Link:
  Entrez Gene 6623 Human
  UniProt ID O76070
• Background: SNCG (also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
• Synonyms: PERSYN, Synuclein gamma, Synoretin, BCSG1, PRSN