gamma Synuclein (SNCG) Mouse Monoclonal Antibody [Clone ID: 1H10D2]

SKU AM06134PU-N

gamma Synuclein (SNCG) mouse monoclonal antibody, clone 1H10D2, Purified

Product Data

• Clone Name: 1H10D2
• Application: IHC, WB
• Recommended Dilution: Western Blot: 1/500 - 1/2000.; Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.; ELISA: 1/10000.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of SNCG expressed in E. Coli.
• Specificity: Recognizes SNCG (breast cancer-specific protein 1).
• Buffer: Ascitic fluid containing 0.03% sodium azide.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. ; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: synuclein gamma
• Database Link:
  O76070
• Background: SNCG (also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
• Synonyms: PERSYN, Synuclein gamma, Synoretin, BCSG1, PRSN

Reference Data