SRA1 Mouse Monoclonal Antibody [Clone ID: 7H1G1]

SKU AM06126SU-N

SRA1 mouse monoclonal antibody, clone 7H1G1, Ascites

Product Data

• Clone Name: 7H1G1
• Application: IHC, WB
• Recommended Dilution: ELISA: 1/10000. ; Western Blot: 1/500-1/2000.; Immunohistochemistry on Paraffin Sections: 1/200-1/1000.
• Reactivity: Human
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of SRA expressed in E. Coli.
• Specificity: Recognizes Steroid receptor RNA activator 1 (SRA).
• Buffer: State: Ascites; State: Ascitic fluid; Preservative: 0.03% Sodium Azide
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. ; Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: steroid receptor RNA activator 1
• Database Link:
  Q9HD15
• Background: Steroid receptor RNA activator 1 (SRA), with 237-amino acid protein (about 27kDa), belongs to the growing family of functional non-coding RNAs. SRA was originally described as the first functional noncoding RNA able to specifically coactivate the activity of steroid receptors. Specifically, SRA exists as both an RNA transcript that forms a complex with steroid receptor coactivator-1 and as a stably expressed protein. Its expression is strongly up-regulated in many human tumors of the breast, uterus, and ovary, suggesting a potential role in pathogenesis. Although coactivation of steroid-dependent transcription by SRA is accompanied by a proliferative response, overexpression is not in itself sufficient to induce turmorigenesis.
• Synonyms: Steroid receptor RNA activator 1

Reference Data