Eph receptor A1 (EPHA1) Mouse Monoclonal Antibody [Clone ID: 5D2]
Product Data | |
Clone Name | 5D2 |
---|---|
Application | ELISA, IHC, WB |
Recommended Dilution | Western Blot: 1/500-1/2000. Immunofluorescence: 1/200-1/1000. ELISA: 1/10000. |
Reactivity | Human |
Antibody Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of EphA1 expressed in E. Coli. |
Specificity | This antibody recognizes Human EphA1. Other species not tested. |
Buffer | PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.03% Sodium Azide |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Shipping | Blue Ice |
Predicted Protein Size | 108 kDa |
Gene Name | EPH receptor A1 |
Database Link | |
Background | EPH receptor A1 (EphA1), with 976-amino acid protein(about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date and their ligands, the ephrins,can be subdivided into two major subclasses, ephrin-A and ephrin-B. Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior, particularly in the nervous system. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis. |
Synonyms | Ephrin type-A receptor 1, EPH, EPHT, EPHT1 |
Reference Data |
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