HIRA Mouse Monoclonal Antibody [Clone ID: 10]

SKU AM05331PU-N

HIRA mouse monoclonal antibody, clone 10, Purified

Product Data

• Clone Name: 10
• Application: WB
• Recommended Dilution: Western blot (5-10 µg/ml).; Positive Control: Mav108 cells expressing recombinant TUP1 protein.
• Reactivity: Saccharomyces cerevisiae
• Antibody Host: Mouse
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Recombinant protein derived from the amino acids 1-200 of yeastt TUP1 protein
• Buffer: PBS containing containing 0.08% Sodium Azide as preservative.; State: Purified; State: Liquid purified IgG fraction.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.; Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Shipping: Blue Ice
• Gene Name: histone cell cycle regulator
• Database Link:
  P54198
• Background: Yeast Tup 1p-Ssn6p repressor complex represents a novel paradigm for transcriptional repression and for the role of chromatin in repression. TUP 1 and SSN6 are involved in repression of several diverse families of genes in yeast, including cell type-specific genes regulated by the alphga2 and a1/alpha2 repressors. Ssn6-Tupl interacts with class I histone deacetylases required for repression, and rfecrfuitment of yeast Tuplp-Ssn6p repressor is associated with localized decreases in histone acetylation.
• Synonyms: DGCR1, HIR

Reference Data