Syndecan 1 (SDC1) Mouse Monoclonal Antibody [Clone ID: B-A38]

CAT#: AM03022AF-N

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Syndecan 1 (SDC1) mouse monoclonal antibody, clone B-A38, Azide Free



USD 336.00


Availability*
2 Weeks

Size
    • 200 ug


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Specifications

Product Data
Clone Name B-A38
Applications FC, IHC
Recommended Dilution Flow Cytometry. 
Immunohistochemistry (1/50).
Reactivity Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen U266 cell line.
Myeloma X63/AG.8653 x Balb/c spleen cells.
Specificity The antibody B-A38 recognizes CD138 (Syndecan-1), a 65-70 kDa heparan sulfate proteoglycan expressed mainly in the epidermis and plasma cells, but also in growth factor-stimulated lymphocytes.
Formulation Azide Free PBS, pH 7.4, 0.2 μm filter sterilized
State: Azide Free
State: Liquid purified Ig fraction
Preservative: None
Concentration lot specific
Purification Ion Exchange Chromatography
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens syndecan 1 (SDC1), transcript variant 1
Background CD138 (syndecan-1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
Synonyms SYND1, SDC1, SDC
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), ECM-receptor interaction
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.