TAC1 Rat Monoclonal Antibody [Clone ID: NC1/34]
Rat monoclonal anti-Substance P antibody, cloneNC1/34, Supernatant
Product Datasheet for 'AM01289SU-N'
|Recommend Dilution||ICC/IF, IHC|
|Immunogen||Substance P conjugated to Bovine Serum Albumin.|
|Purification||Liquid Tissue Culture Supernatant containing 0.09% Thiomersal Supernatant|
|Predicted Protein Size||~9.2 kDa|
|Gene Name||tachykinin precursor 1|
|Background||Substance P (SP) is currently thought to be one of the most important neurotransmitters and neurotransmitters in the brain. It is an undecapeptide belonging to the tachykinin family, which consists of excitatory neuropeptides synthesised in neuronal and glial cells of the human central and peripheral nervous system. Substance P, Neurokinin A, Neuropeptide K, and Neuropeptide gamma are all generated by post-translation cleavage of the precursor Protachykinin-1. Substance P forms the major endogenous ligand for Neurokinin 1 Receptor. The pharmacology of Substance P has been associated with a number of neurological and psychiatric disorders, namely nociception, migraine, asthma, nausea, inflammatory bowel syndrome, urinary incontinence, anxiety and depression. It has also been linked to obesity.|
|Synonyms||Hs.2563; NK2; NKNA; NPK; TAC2|
|Protein Families||Druggable Genome, Secreted Protein|
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