p75 NGF Receptor (NGFR) (1-160) Mouse Monoclonal Antibody [Clone ID: NGFR5]

SKU AM00235BT-N

p75 NGF Receptor (NGFR) (1-160) mouse monoclonal antibody, clone NGFR5, Biotin

Product Data

• Clone Name: NGFR5
• Application: FC
• Recommended Dilution: Indirect immunofluorescence analysis by Flow cytometry: 1:200 as starting point.
• Reactivity: Feline, Ferret, Human, Primate, Rabbit
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified CD271 protein isolated from human melanoma cell line A875
• Specificity: This antibody recognizes CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily. The epitope is localized within ammino acids 1 - 160.
• Buffer: Phosphate buffered saline (PBS); Label: Biotin; State: Liquid purified Ig fraction; Preservative: 15 mM sodium azide, approx. pH 7.4; Label: Conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.
• Concentration: lot specific
• Conjugation: Biotin
• Storage: Store undiluted at 2-8°C.; DO NOT FREEZE!
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: nerve growth factor receptor
• Database Link:
  P08138
• Background: CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
• Synonyms: TNFRSF16

Reference Data