Traumatic brain injury (TBI) results from external forces applied to the brain in the form of head impact, acceleration, deceleration, or object penetrance. TBI is most often classified as mild, moderate, or severe based on post-injury symptom profile. Heterogeneity in TBI symptom presentation, however, represents a substantial obstacle for its efficient diagnosis and treatment. The discovery and validation of biomarkers that reliably predict both tissue damage severity and patient outcomes could substantially improve clinical care.
Biomarkers for Traumatic Brain Injury: A Short Overview
- Introduction to TBI and how TBI markers escape the CNS
- 3 key considerations for TBI biomarker validation
- List of Plasma biomarkers and its predictive modalities
- Future of diagnostic biomarkers in TBI