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Primary Antibodies
LGR5 mouse monoclonal antibody, clone OTI2A2
| Applications | FC, IF, IHC, IP, WB |
| Reactivities | Human, Mouse, Rat |
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Target Symbol
- VSNL1 (269)
- ALK (264)
- KLK8 (233)
- MAP2K1 (217)
- TP53 (189)
- CD4 (188)
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- NME1 (167)
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- OTC (123)
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- LIPG (118)
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- ABCB1 (112)
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- PIK3C2A (111)
- CD5 (106)
- TOP2A (105)
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- IDO1 (61)
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- BTLA (60)
- CCT8L2 (60)
- GFAP (60)
- SPG7 (60)
- TYMP (60)
- VWF (60)
- BBOX1 (59)
- L1CAM (59)
- CNOT4 (58)
- GAPDH (58)
- KRAS (58)
- CDH1 (57)
- HIST1H3A (57)
- PIK3CG (57)
- AFAP1 (56)
- KRT7 (56)
- MAPK1 (56)
- NAB1 (56)
- ZNF365 (56)
- HADH (55)
- MS4A1 (55)
- MSR1 (55)
- PNMT (55)
- CBX8 (54)
- CD80 (54)
- FGG (54)
- MMP13 (54)
- VBP1 (54)
- CD1C (53)
Reactivities
- Human (94512)
- Mouse (48041)
- Rat (40204)
- Monkey (4130)
- Dog (3121)
- Bovine (1178)
- Canine (886)
- Porcine (666)
- Rabbit (471)
- Chicken (419)
- Hamster (295)
- Primate (231)
- Equine (187)
- Zebrafish (187)
- Xenopus (170)
- Sheep (139)
- Feline (112)
- Guinea Pig (91)
- Bat (88)
- Drosophila (80)
- Chimpanzee (71)
- Yeast (71)
- Pig (68)
- All Species (59)
- Mammalian (58)
- SARS-CoV-2 (56)
- Human Mouse (55)
- Goat (52)
- Escherichia coli (50)
- Murine (47)
- Bakers Yeast (42)
- Human Mouse Rat (42)
- Fish (35)
- Bacteria (34)
- Cow (34)
- Virus (28)
- Bacillus sp. (24)
- Amphibian (21)
- Rat Other (Wide Range) (19)
- Schistosoma japonicum (18)
- Opossum (16)
- A. victoria (15)
- Baboon (15)
- C. elegans (15)
- Frog (14)
- Macaque (14)
- Mammal (13)
- Candida (12)
- Canis (12)
- Enterobacter (12)
- Horse (12)
- Human Rat (12)
- Aspergillus (11)
- Avian (11)
- Saccharomyces cerevisiae (11)
- Insect (10)
- Other (Wide Ratange) (10)
- Chinese Hamster (9)
- Guinea Porcine (9)
- Mink (9)
- Orang-Utan (9)
- Plant (9)
- Rat. Not yet tested on other species (9)
- Streptococcus Pyogenes (9)
- African clawed frog (8)
- Birds (8)
- Gorilla (8)
- Rhesus macaque (8)
- Alcaligenes (7)
- Mk (7)
- Penicillium (7)
- Quail (7)
- Transfected (7)
- Drosph (6)
- Jack Bean (6)
- Leuconostoc (6)
- Mouse (Negative) (6)
- Other (6)
- Pigeon (6)
- Ratange) (6)
- SARS-CoV (6)
- mCherry (6)
- (Wide (5)
- Broad (5)
- Cucurbita (5)
- Expected from seq similarity: Human (5)
- Ferret (5)
- Guinea pig (5)
- Human (Identities = 100% (5)
- M (5)
- Maize (5)
- Mousse (5)
- Photobacterium fischerii (5)
- Primat (5)
- Rat (Negative) (5)
- Rhesus Monkey (5)
- Snake (5)
- Test: Human. Expected from seq similarity: Human (5)
- tdTomato (5)
- Bacillus amyloliquefacies (4)
- Beluga (4)
- Carica papaya (4)
- Human (Negative) (4)
- Lima Bean (4)
- Mousek (4)
- Myrothecium (4)
- Photinus pyralis (4)
- Rat. Other species not tested yet (4)
- Red Fluorescent (4)
- Rhizopus (4)
- Ricinus communis (4)
- Soy Bean (4)
- Sweet Potato (4)
- Turkey (4)
- broad range (4)
- Deer (3)
- Duck (3)
- Fruit Fly (3)
- Gerbil (3)
- Horsereddish (3)
- Human. Other species not yet tested (3)
- Lactococcus lacti (3)
- Mouse and Rat (3)
- Mycobacteria (3)
- P. testosteroni (3)
- Porcin (3)
- Positives = 100% (3)
- Primate (Negative) (3)
- Rat Mk (3)
- Staphylococcus aureus (3)
- StrepII-Tag (3)
- Streptococcus (3)
- Ustilago maydis (3)
- not Mouse (3)
- not react with Mouse (3)
- var. (3)
- Arabidopsis thaliana (2)
- Bacteriophage P1 (2)
- Burkholderia (2)
- Burkholderia cenocepacia (2)
- C.elegans (2)
- Carp (2)
- Coral (2)
- Dictyostelium (2)
- Drosophilia (2)
- EGFP (2)
- Firefly (2)
- Fruit fly (Drosophila melanogaster) (2)
- Fungus (2)
- GFP (2)
- Guinea porcine (2)
- HIV (2)
- HPV11 (2)
- Human (weak) (2)
- Human Vertebrates (2)
- Human and Mouse (2)
- Human:Lys380 (2)
- Kangaroo (2)
- Marmoset (2)
- Mouse: Ser79 (2)
- Murin (2)
- Non-species specific (2)
- Ovine (2)
- Positives = 100%) (2)
- R (2)
- Rat. Other species not yet tested (2)
- Salmonid (2)
- Scallop porcine (2)
- Squirrel (2)
- Swine (2)
- Test: Human (2)
- V5-tagged proteins (2)
- Xenopu (2)
- YFP (2)
- and Frog (2)
- (1)
- &beta (1)
- A Broad Range Of Species (1)
- Acetylated lysine residues (1)
- African Green Monkey (1)
- Algal (1)
- Atlantic Hagfish (Myxine glutinosa) (1)
- BBC6 (1)
- BCL2L8 (1)
- Bcl-2-binding component 6 (1)
- Bcl-2-like protein 8 (1)
- Bcl-XL/Bcl-2-associated death promoterTarget/SpecificityThis Bad anti (1)
- Bcl2 antagonist of cell death (1)
- Bison (1)
- Boar (1)
- Bovine) (1)
- Brugia malayi (1)
- Caenorhabditis elegans (1)
- Canine and Monkey proteins (1)
- Canine. Other species not yet tested (1)
- Cellulomonas (1)
- ChiChickenen (1)
- Chicken (weak) (1)
- Chicken) (1)
- Chimpanzee and Chicken (1)
- Chimpanzee and Macaque (1)
- Cod (1)
- CrayFish (1)
- DYKDDDDK-tagged proteins (1)
- Detects Rab35 in cell lysates and transfected cells by Western blot. (1)
- Dosophila (1)
- DrosOp (1)
- Drosop (1)
- Drosoph (1)
- Drosophila (weak) (1)
- E.coli (GroEl) (1)
- Eukaryotes (1)
- Fish (carp) (1)
- G (1)
- GP (1)
- Golden Hamster (1)
- Golden Syrian Hamster (1)
- H (1)
- H. pylori (1)
- H:S157 (1)
- H:S178 (1)
- H:S219 (1)
- H:S272 (1)
- H:S76 (1)
- H:T230 (1)
- H:T308 (1)
- H:Y452 (1)
- H:Y992 (1)
- HA-tag proteins (1)
- HIV-1 (1)
- Hamste (1)
- Horseradish Peroxidase (1)
- Hu (1)
- Human (Alpha specific) (1)
- Human (Predicted: Mouse (1)
- Human (Predicted: Pig (1)
- Human (Recognizes the &alpha (1)
- Human (recognizes &Delta (1)
- Human HeLa and LNCaP cells (1)
- Human and fusion proteins in All Species (1)
- Human papilloma virus (1)
- Human. Not yet tested on other species (1)
- Human. Very limited cross-reactivity to other species (1)
- Human.Mouse (1)
- Human: Ser19 (1)
- Human: Ser23 (1)
- Human: Ser246 (1)
- Human: Ser383 (1)
- Human: Ser524 (1)
- Human: Ser73 (1)
- Human: Ser80 (1)
- Human: Ser852 (1)
- Human: Ser9 (1)
- Human: Thr209 (1)
- Human: Thr507 (1)
- Human: Thr693 (1)
- Human: Tyr1003 (1)
- Human: Tyr173 (1)
- Human: Tyr205/222 (1)
- Human: Tyr410 (1)
- Human: Tyr463/466 (1)
- Human: Tyr530 (1)
- Human: Tyr551 (1)
- Human: Tyr699 (1)
- Human: Tyr708 (1)
- Human: Tyr771 (1)
- Human: Tyr849 (1)
- Human:S167 (1)
- Human:S346 (1)
- Human:Ser784 (1)
- Human:Tyr1213 (1)
- Human:Tyr307 (1)
- Human:Y1355 (1)
- HumanCalculated MW18392 DaBad Antibody (Center) - Additional infoGene ID 572Other NamesBAD (1)
- HumanMouse (1)
- HumannMouse (1)
- Hydra (1)
- Inverte (1)
- It does not react against any human protein. (1)
- Lamprey (1)
- M:S153 (1)
- M:S178 (1)
- M:S218 (1)
- M:S272 (1)
- M:S74 (1)
- M:T226 (1)
- M:T308 (1)
- M:Y441 (1)
- M:Y990 (1)
- Mammal (Negative) (1)
- Manducasexta (1)
- Middle East respiratory Syndrome coronavirus (1)
- Most Species (1)
- Mouse (Predicted: Bovine) (1)
- Mouse (Predicted: Chimpanzee) (1)
- Mouse Rat (1)
- Mouse. Expected from seq similarity: Human (1)
- Mouse: Ser19 (1)
- Mouse: Ser23 (1)
- Mouse: Ser246 (1)
- Mouse: Ser847 (1)
- Mouse: Ser9 (1)
- Mouse: Thr497 (1)
- Mouse: Thr695 (1)
- Mouse: Tyr1001 (1)
- Mouse: Tyr173 (1)
- Mouse: Tyr203/223 (1)
- Mouse: Tyr346 (1)
- Mouse: Tyr414 (1)
- Mouse: Tyr463/466 (1)
- Mouse: Tyr527 (1)
- Mouse: Tyr551 (1)
- Mouse: Tyr706 (1)
- Mouse: Tyr849 (1)
- Mouse:Ser784 (1)
- Mouse:T452 (1)
- Mouse:Thr641 (1)
- Mouse:Tyr1213 (1)
- Mouse:Tyr307 (1)
- Mustel (1)
- Mustelid (1)
- N-isoforms) (1)
- Olive Baboon (1)
- Other(Wide (1)
- Plants (1)
- Pollen (1)
- Porcine (Pig) (1)
- Positives = 100%); Mouse (Identities = 100% (1)
- Positives = 100%);Rat (Identities = 100% (1)
- Potoroo (1)
- Pr (1)
- Pri (1)
- Prima (1)
- Pseudomonas (1)
- Pufferfish (1)
- R:S154 (1)
- R:S207 (1)
- R:S301 (1)
- R:S76 (1)
- R:T226 (1)
- R:T308 (1)
- R:Y441 (1)
- Rabbi (1)
- Rabbit (Negative) (1)
- Rabbit. Dog (1)
- Rat Monkey (1)
- Rat P (1)
- Rat and All Species (1)
- Rat and Dog (1)
- Rat. Chicken (1)
- Rat. Expected from seq similarity: Human (1)
- Rat. Not tested in other species (1)
- Rat. Not yet tested in other species (1)
- Rat. Other species not tested (1)
- Rat: Ser19 (1)
- Rat: Ser23 (1)
- Rat: Ser523 (1)
- Rat: Ser79 (1)
- Rat: Ser847 (1)
- Rat: Ser9 (1)
- Rat: Thr508 (1)
- Rat: Thr694 (1)
- Rat: Tyr1004 (1)
- Rat: Tyr203/223 (1)
- Rat: Tyr346 (1)
- Rat: Tyr463/ (1)
- Rat: Tyr508 (1)
- Rat: Tyr706 (1)
- Rat: Tyr770 (1)
- Rat: Tyr850 (1)
- Rat:Ser784 (1)
- Rat:Tyr1213 (1)
- Rat:Tyr552 (1)
- Ray (1)
- Red Fluorescent Protein (1)
- Rhesus (1)
- Rice yellow mottle virus (1)
- Rouse (1)
- S. cerevisiae (1)
- S. cerevisiae (lower) (1)
- S. typhimurium (1)
- Sea Urchin (1)
- Short-tailed Opossum (1)
- Silk Worm (1)
- SimianIVE (1)
- Spinach (1)
- Spiny Dogfish Shark (Squalus acanthias) (1)
- Squirrel Monkey (1)
- T. spiralis (1)
- T7-tag proteins (1)
- Tadpole (1)
- Tobacco (1)
- Tobacco hornworm (1)
- Tomato (1)
- Trout (1)
- VSV-G-tagged proteins (1)
- Venus (1)
- Vervet Monkey (1)
- WB: 1:500~1:1000 ELISA: 1:10000 (1)
- WB: 1:500~1:1000 ELISA: 1:5000 (1)
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000 (1)
- Weakly Cross-Reactive with Mouse (1)
- Wolffish (1)
- Xe (1)
- Xenopus (Negative) (1)
- Xenopus (weak) (1)
- Xenopus Tropicalis (1)
- ZebraFish (1)
- and &gamma (1)
- and Fruit fly (1)
- c-Myc (1)
- chlamydomonas (1)
- isoforms) (1)
- mOrange (1)
- mPlum (1)
- mRFP (1)
- mStrawberry and tdTomato (1)
- many mammalian (1)
- non human primate (1)
- non-human primates (1)
- not Mouse or Rat (1)
- other species (1)
- partial reactivity to Mouse and Rat (1)
- recombinant (1)
- red fluorescent (1)
- uman: Tyr352 (1)
- weakly cross-reactive with Mouse (1)
- white fly (1)
- yeast (1)
Antibody Hosts
Knockout (KO) Validation
Conjugates
Modifications
Isotypes
- IgG1 (33850)
- IgG (33774)
- IgG2a (8648)
- IgG2b (7492)
- Ig (4898)
- IgG1, kappa (204)
- IgG3 (182)
- IgM (140)
- IgG2 (89)
- IgY (72)
- IgG2b, kappa (44)
- IgG2a, kappa (42)
- IgG2c (13)
- IgM, kappa (11)
- IgG3, kappa (6)
- IgG1, lambda (3)
- cocktail (3)
- IgG1/IgG2b (2)
- IgA (1)
- IgA, kappa (1)
- IgG fraction (1)
- IgG1/IgK (1)
- IgG2, alpha (1)
- IgG2, kappa (1)
- IgG2b, lambda (1)
- IgG3/IgG1 (1)
- IgG4 (1)
Clonalities
Availabilities
Citations
Families
- Druggable Genome (46443)
- Transmembrane (17147)
- Transcription Factors (13576)
- Secreted Protein (7008)
- ES Cell Differentiation/IPS (5602)
- Protein Kinase (5403)
- Stem cell - Pluripotency (3210)
- Protease (3108)
- Adult stem cells (1374)
- Nuclear Hormone Receptor (985)
- Embryonic stem cells (969)
- GPCR (958)
- Phosphatase (828)
- Cancer stem cells (708)
- Induced pluripotent stem cells (604)
- Stem cell relevant signaling - JAK/STAT signaling pathway (515)
- Ion Channels: Other (475)
- Stem cell relevant signaling - DSL/Notch pathway (374)
- P450 (352)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (269)
- Ion Channels: Potassium (208)
- Stem cell relevant signaling - Wnt Signaling pathway (151)
- Ion Channels: Cys-loop Receptors (142)
- Ion Channels: Transient receptor potential (95)
- Ion Channels: Glutamate Receptors (84)
- Ion Channels: ATP Receptors (23)
- Ion Channels: Sodium (22)
- Ion Channels: Cyclic nucleotide gated (13)
- Ion Channels: Calcium (9)
Pathways
- Metabolic pathways (7021)
- Pathways in cancer (5800)
- MAPK signaling pathway (3891)
- Focal adhesion (3113)
- Prostate cancer (2695)
- Neurotrophin signaling pathway (2489)
- T cell receptor signaling pathway (2409)
- Cytokine-cytokine receptor interaction (2369)
- Colorectal cancer (2276)
- ErbB signaling pathway (2157)
- Regulation of actin cytoskeleton (2155)
- Toll-like receptor signaling pathway (2147)
- Pancreatic cancer (2118)
- Chronic myeloid leukemia (2020)
- Cell cycle (2014)
- Melanoma (1996)
- Insulin signaling pathway (1874)
- Glioma (1870)
- Chemokine signaling pathway (1865)
- Endometrial cancer (1840)
- Cell adhesion molecules (CAMs) (1828)
- Non-small cell lung cancer (1815)
- Progesterone-mediated oocyte maturation (1798)
- Bladder cancer (1765)
- B cell receptor signaling pathway (1726)
- Jak-STAT signaling pathway (1655)
- GnRH signaling pathway (1641)
- Wnt signaling pathway (1629)
- Endocytosis (1610)
- Apoptosis (1588)
- Fc epsilon RI signaling pathway (1584)
- Leukocyte transendothelial migration (1579)
- Acute myeloid leukemia (1548)
- Renal cell carcinoma (1528)
- Natural killer cell mediated cytotoxicity (1515)
- Hematopoietic cell lineage (1496)
- Small cell lung cancer (1458)
- VEGF signaling pathway (1453)
- Alzheimer's disease (1375)
- Fc gamma R-mediated phagocytosis (1370)
- p53 signaling pathway (1361)
- Gap junction (1310)
- Adherens junction (1294)
- Huntington's disease (1238)
- Oocyte meiosis (1212)
- Melanogenesis (1199)
- Amyotrophic lateral sclerosis (ALS) (1158)
- Calcium signaling pathway (1156)
- Epithelial cell signaling in Helicobacter pylori infection (1149)
- Ubiquitin mediated proteolysis (1138)
- Purine metabolism (1092)
- Thyroid cancer (1088)
- Tight junction (1061)
- Neuroactive ligand-receptor interaction (1058)
- Adipocytokine signaling pathway (1047)
- Axon guidance (984)
- mTOR signaling pathway (939)
- Pyrimidine metabolism (928)
- NOD-like receptor signaling pathway (921)
- Long-term depression (901)
- Long-term potentiation (879)
- RIG-I-like receptor signaling pathway (878)
- Vascular smooth muscle contraction (873)
- Pathogenic Escherichia coli infection (846)
- TGF-beta signaling pathway (823)
- Parkinson's disease (797)
- Type II diabetes mellitus (763)
- Systemic lupus erythematosus (736)
- Antigen processing and presentation (731)
- Basal cell carcinoma (718)
- Complement and coagulation cascades (716)
- Glycolysis / Gluconeogenesis (685)
- Prion diseases (670)
- Primary immunodeficiency (659)
- Lysosome (620)
- Cytosolic DNA-sensing pathway (616)
- Dorso-ventral axis formation (615)
- Arginine and proline metabolism (602)
- Viral myocarditis (595)
- Hypertrophic cardiomyopathy (HCM) (590)
- Nucleotide excision repair (576)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (572)
- Dilated cardiomyopathy (569)
- PPAR signaling pathway (553)
- Olfactory transduction (531)
- Spliceosome (526)
- Oxidative phosphorylation (524)
- Valine (509)
- Hedgehog signaling pathway (501)
- Phosphatidylinositol signaling system (480)
- leucine and isoleucine degradation (480)
- Type I diabetes mellitus (453)
- ECM-receptor interaction (452)
- Tryptophan metabolism (447)
- Drug metabolism - cytochrome P450 (442)
- Metabolism of xenobiotics by cytochrome P450 (436)
- Proteasome (433)
- RNA degradation (433)
- Glycerolipid metabolism (412)
- Lysine degradation (412)
- Notch signaling pathway (411)
- Fatty acid metabolism (391)
- Pyruvate metabolism (390)
- Autoimmune thyroid disease (386)
- Allograft rejection (376)
- Arachidonic acid metabolism (376)
- Inositol phosphate metabolism (376)
- Graft-versus-host disease (371)
- Tyrosine metabolism (369)
- DNA replication (364)
- Base excision repair (357)
- Vibrio cholerae infection (351)
- Glutathione metabolism (345)
- Propanoate metabolism (337)
- Alanine (327)
- Butanoate metabolism (327)
- Mismatch repair (327)
- aspartate and glutamate metabolism (327)
- Drug metabolism - other enzymes (310)
- One carbon pool by folate (310)
- Histidine metabolism (307)
- Cardiac muscle contraction (306)
- Retinol metabolism (287)
- Homologous recombination (285)
- ABC transporters (269)
- Maturity onset diabetes of the young (260)
- Fructose and mannose metabolism (251)
- Ribosome (251)
- Glycine (250)
- serine and threonine metabolism (250)
- Cysteine and methionine metabolism (248)
- beta-Alanine metabolism (235)
- Amino sugar and nucleotide sugar metabolism (233)
- Sphingolipid metabolism (216)
- Glycerophospholipid metabolism (215)
- Citrate cycle (TCA cycle) (213)
- Renin-angiotensin system (205)
- Regulation of autophagy (204)
- SNARE interactions in vesicular transport (195)
- Linoleic acid metabolism (186)
- Asthma (178)
- Pentose phosphate pathway (178)
- Porphyrin and chlorophyll metabolism (177)
- Starch and sucrose metabolism (177)
- Circadian rhythm - mammal (174)
- Nitrogen metabolism (160)
- RNA polymerase (157)
- Basal transcription factors (153)
- Nicotinate and nicotinamide metabolism (150)
- Non-homologous end-joining (143)
- Galactose metabolism (141)
- Terpenoid backbone biosynthesis (139)
- Aminoacyl-tRNA biosynthesis (137)
- Androgen and estrogen metabolism (136)
- Primary bile acid biosynthesis (131)
- N-Glycan biosynthesis (130)
- Other glycan degradation (129)
- Phenylalanine metabolism (124)
- Fatty acid elongation in mitochondria (123)
- Taste transduction (121)
- Ascorbate and aldarate metabolism (111)
- Ether lipid metabolism (109)
- Folate biosynthesis (109)
- Selenoamino acid metabolism (103)
- Caffeine metabolism (101)
- Glyoxylate and dicarboxylate metabolism (99)
- Sulfur metabolism (97)
- Methane metabolism (95)
- Glycosaminoglycan degradation (91)
- Limonene and pinene degradation (79)
- Synthesis and degradation of ketone bodies (78)
- Biosynthesis of unsaturated fatty acids (72)
- Riboflavin metabolism (66)
- Pentose and glucuronate interconversions (62)
- C21-Steroid hormone metabolism (57)
- Thiamine metabolism (57)
- Glycosphingolipid biosynthesis - lacto and neolacto series (54)
- Keratan sulfate biosynthesis (53)
- O-Glycan biosynthesis (53)
- Fatty acid biosynthesis (51)
- Pantothenate and CoA biosynthesis (51)
- alpha-Linolenic acid metabolism (49)
- Glycosphingolipid biosynthesis - ganglio series (46)
- Taurine and hypotaurine metabolism (45)
- leucine and isoleucine biosynthesis (40)
- Vitamin B6 metabolism (37)
- Heparan sulfate biosynthesis (34)
- Chondroitin sulfate biosynthesis (32)
- Glycosphingolipid biosynthesis - globo series (32)
- Cyanoamino acid metabolism (30)
- Steroid biosynthesis (29)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (25)
- Phenylalanine (23)
- tyrosine and tryptophan biosynthesis (23)
- D-Glutamine and D-glutamate metabolism (20)
- Protein export (19)
- Lysine biosynthesis (13)
- Ubiquinone and other terpenoid-quinone biosynthesis (12)
- Lipoic acid metabolism (6)
- O-Mannosyl glycan biosynthesis (5)
- Biotin metabolism (3)
- D-Arginine and D-ornithine metabolism (2)